How Dopamine Shapes Representations in Auditory Cortex

نویسندگان

  • Sebastian Puschmann
  • Tina Weis
  • Christiane M. Thiel
چکیده

The neural representation of sound in the auditory cortex is not invariably predetermined by its acoustical properties, but it is constantly reshaped while the listener acquires new experiences. Such plastic changes are a prerequisite for lifelong learning and allow some degree of rehabilitation after brain injuries. Several neurotransmitter systems modulate these plastic changes. In this paper, we focus on how the neurotransmitter dopamine modulates learning-related plasticity in auditory cortex, and how animal and human research can complement each other in providing an experimental approach that has relevance for studying mechanisms of recovery of function.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Feedback that confirms reward expectation triggers auditory cortex activity.

Associative learning studies have shown that the anticipation of reward and punishment shapes the representation of sensory stimuli, which is further modulated by dopamine. Less is known about whether and how reward delivery activates sensory cortices and the role of dopamine at that time point of learning. We used an appetitive instrumental learning task in which participants had to learn that...

متن کامل

Language Experience Shapes Processing of Pitch Relevant Information in the Human Brainstem and Auditory Cortex: Electrophysiological Evidence.

Pitch is a robust perceptual attribute that plays an important role in speech, language, and music. As such, it provides an analytic window to evaluate how neural activity relevant to pitch undergo transformation from early sensory to later cognitive stages of processing in a well coordinated hierarchical network that is subject to experience-dependent plasticity. We review recent evidence of l...

متن کامل

Experience-dependent plasticity in pitch encoding: from brainstem to auditory cortex.

Linguistic and musical pitch provide an analytic window to evaluate how neural representations of important pitch attributes of a sound undergo transformation from early sensory to later cognitive stages of processing in the human brain, and how pitch-relevant experience shapes these representations. These pitch attributes are shaped differentially depending on their functional relevance to a l...

متن کامل

Task reward structure shapes rapid receptive field plasticity in auditory cortex.

As sensory stimuli and behavioral demands change, the attentive brain quickly identifies task-relevant stimuli and associates them with appropriate motor responses. The effects of attention on sensory processing vary across task paradigms, suggesting that the brain may use multiple strategies and mechanisms to highlight attended stimuli and link them to motor action. To better understand factor...

متن کامل

Dopamine-mediated reinforcement learning signals in the striatum and ventromedial prefrontal cortex underlie value-based choices.

A large body of evidence exists on the role of dopamine in reinforcement learning. Less is known about how dopamine shapes the relative impact of positive and negative outcomes to guide value-based choices. We combined administration of the dopamine D(2) receptor antagonist amisulpride with functional magnetic resonance imaging in healthy human volunteers. Amisulpride did not affect initial rei...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014